BDBM732838 N-(4-chlorophenyl)-5-[4-cyano-5-methoxy- 2-[(3S)-3-(morpholinomethyl)-3,4-dihydro- 1H-isoquinoline-2-carbonyl]phenyl]-N-[(2- cyanophenyl)methyl]-1,2-dimethyl-pyrrole- 3-carboxamide::US20250115577, Compound 59

SMILES COc1cc(-c2cc(C(=O)N(Cc3ccccc3C#N)c3ccc(Cl)cc3)c(C)n2C)c(C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)cc1C#N

InChI Key InChIKey=UHMRJWXBIDENPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 732838   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732838(N-(4-chlorophenyl)-5-[4-cyano-5-methoxy- 2-[(3S)-3...)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732838(N-(4-chlorophenyl)-5-[4-cyano-5-methoxy- 2-[(3S)-3...)
Affinity DataIC50: 3.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent