BDBM732836 5-[4-cyano-5-methoxy-2-[(3S)-3- (morpholinomethyl)-3,4-dihydro-1H- isoquinoline-2-carbonyl]phenyl]-N-(4- hydroxyphenyl)-N-[(3-methoxy-2-methyl- phenyl)methyl]-1,2-dimethyl-pyrrole-3- carboxamide::US20250115577, Compound 58

SMILES COc1cc(-c2cc(C(=O)N(Cc3cccc(OC)c3C)c3ccc(O)cc3)c(C)n2C)c(C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)cc1C#N

InChI Key InChIKey=LNBHKASEEPYDHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 732836   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732836(5-[4-cyano-5-methoxy-2-[(3S)-3- (morpholinomethyl)...)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732836(5-[4-cyano-5-methoxy-2-[(3S)-3- (morpholinomethyl)...)
Affinity DataIC50: 3.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent