BDBM732830 5-[5-fluoro-2-[(3S)-3-(morpholinomethyl)- 3,4-dihydro-1H-isoquinoline-2- carbonyl]phenyl]-N-(4-hydroxyphenyl)-N- [(3-methoxy-2-methyl-phenyl)methyl]-1,2- dimethyl-pyrrole-3-carboxamide::US20250115577, Compound 52

SMILES COc1cccc(CN(C(=O)c2cc(-c3cc(F)ccc3C(=O)N3Cc4ccccc4C[C@H]3CN3CCOCC3)n(C)c2C)c2ccc(O)cc2)c1C

InChI Key InChIKey=CGGFETJEQJPIIS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 732830   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732830(5-[5-fluoro-2-[(3S)-3-(morpholinomethyl)- 3,4-dihy...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732830(5-[5-fluoro-2-[(3S)-3-(morpholinomethyl)- 3,4-dihy...)
Affinity DataIC50: 3.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2 [G101V](Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732830(5-[5-fluoro-2-[(3S)-3-(morpholinomethyl)- 3,4-dihy...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent