BDBM732825 N-(4-cyanophenyl)-5-[4-(difluoromethoxy)- 5-fluoro-2-[(3S)-3-(morpholinomethyl)-3,4- dihydro-1H-isoquinoline-2- carbonyl]phenyl]-N-[(3-methoxy-2-methyl- phenyl)methyl]-1,2-dimethyl-pyrrole-3- carboxamide::US20250115577, Compound 44

SMILES COc1cccc(CN(C(=O)c2cc(-c3cc(F)c(OC(F)F)cc3C(=O)N3Cc4ccccc4C[C@H]3CN3CCOCC3)n(C)c2C)c2ccc(C#N)cc2)c1C

InChI Key InChIKey=JANCNAUIJVKDKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 732825   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732825(N-(4-cyanophenyl)-5-[4-(difluoromethoxy)- 5-fluoro...)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732825(N-(4-cyanophenyl)-5-[4-(difluoromethoxy)- 5-fluoro...)
Affinity DataIC50: 3.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent