BDBM732809 N-pyrimidin-4-yl-6-[rac- (1S,2S,4S)-2-pyrrolidin-1-yl- 4-[3-(trifluoromethoxy)- phenyl]cyclohexyl]amino]- pyridine-3-sulfonamide formate salt::US20250115576, Example 9

SMILES O=S(=O)(Nc1ccncn1)c1ccc(N[C@H]2CC[C@H](c3cccc(OC(F)(F)F)c3)C[C@@H]2N2CCCC2)nc1

InChI Key InChIKey=SZOAHGGOZGLGNA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 732809   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM732809(N-pyrimidin-4-yl-6-[rac- (1S,2S,4S)-2-pyrrolidin-1...)
Affinity DataIC50: 4.11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM732809(N-pyrimidin-4-yl-6-[rac- (1S,2S,4S)-2-pyrrolidin-1...)
Affinity DataIC50: 0.664nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent