BDBM732748 4-((5S,7S)-2,2-difluoro-8-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)-8-azaspiro[4.5]decan-7-yl)benzoic acid or 4-((5R,7S)-2,2-difluoro-8-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)-8-azaspiro[4.5]decan-7-yl)benzoic acid::US20250115572, Ex-18

SMILES COc1cc(C)c2[nH]ccc2c1CN1CCC2(CCC(F)(F)C2)C[C@H]1c1ccc(C(=O)O)cc1

InChI Key InChIKey=DJJCYEIUXJQPAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 732748   

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM732748(4-((5S,7S)-2,2-difluoro-8-((5-methoxy-7-methyl-1H-...)
Affinity DataIC50: 3.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent