BDBM731716 US20250114338, Example 149::cyclopentyl-[(1R,3R)-1-[2,6- difluoro-4-[2-[3- (fluoromethyl)azetidin-1- yl]ethoxy]phenyl]-3-methyl- 1,3,4,9-tetrahydropyrido[3,4- b]indol-2-yl]methanone

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(OCCN3CC(CF)C3)cc2F)N1C(=O)C1CCCC1

InChI Key InChIKey=XENFQQCXGHSXJF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731716   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM731716(cyclopentyl-[(1R,3R)-1-[2,6- difluoro-4-[2-[3- (fl...)
Affinity DataEC50:  2.16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
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