BDBM731689 (1R,3R)-1-(2,6-difluoro-4-(2- ((R)-3-methylpyrrolidin-1- yl)ethoxy)phenyl)-2-(2- fluoro-2-methylpropyl)-3- methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indole::US20250114338, Example 141

SMILES C[C@@H]1CCN(CCOc2cc(F)c([C@@H]3c4[nH]c5ccccc5c4C[C@@H](C)N3CC(C)(C)F)c(F)c2)C1

InChI Key InChIKey=IAFGNGJVZAFBNO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731689   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM731689((1R,3R)-1-(2,6-difluoro-4-(2- ((R)-3-methylpyrroli...)
Affinity DataEC50:  0.151nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent