BDBM731679 (1R,3R)-1-[4-(azetidin-3- yloxy)-2,6-difluoro-phenyl]- 2-(2-fluoro-2-methyl-propyl)- 3-methyl-1,3,4,9- tetrahydropyrido[3,4-b]indole::US20250114338, Example 132

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(OC3CNC3)cc2F)N1CC(C)(C)F

InChI Key InChIKey=LUXOYNKNOZGOQZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731679   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM731679((1R,3R)-1-[4-(azetidin-3- yloxy)-2,6-difluoro-phen...)
Affinity DataEC50:  0.310nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent