BDBM731678 ((1S,3R)-1-(2,6-difluoro-4-(2- (3-(fluoromethyl)azetidin-1- yl)ethoxy)phenyl)-2-(2- fluoro-2-methylpropyl)- 2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-3- yl)methanol::US20250114338, Example 131

SMILES CC(C)(F)CN1[C@@H](CO)Cc2c([nH]c3ccccc23)[C@@H]1c1c(F)cc(OCCN2CC(CF)C2)cc1F

InChI Key InChIKey=TUIZVHHDZMNJSR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731678   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM731678(((1S,3R)-1-(2,6-difluoro-4-(2- (3-(fluoromethyl)az...)
Affinity DataEC50:  0.146nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent