BDBM731416 3-(4-acrylamidobenzamido)-6,6-dimethyl-N-(2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxamide ::US12281126, Compound 207

SMILES C=CC(=O)Nc1ccc(C(=O)Nc2n[nH]c3c2CN(C(=O)NC2CN(C)Cc4ccccc42)C3(C)C)cc1

InChI Key InChIKey=HUSCDVQJPZERFH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 731416   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM731416(3-(4-acrylamidobenzamido)-6,6-dimethyl-N-(2-methyl...)
Affinity DataIC50: 3.41E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
Go to US Patent

LigandPNGBDBM731416(3-(4-acrylamidobenzamido)-6,6-dimethyl-N-(2-methyl...)
Affinity DataIC50: 15.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
Go to US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM731416(3-(4-acrylamidobenzamido)-6,6-dimethyl-N-(2-methyl...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
Go to US Patent