BDBM731345 US12281099, Example I-063

SMILES Nc1cccc2c(C3OC(=O)c4ccc(O)cc43)c(CNCc3ccc4cc[nH]c4c3)[nH]c12

InChI Key InChIKey=WRDHUSSJXJXEKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 731345   

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM731345(US12281099, Example I-063)
Affinity DataIC50: 2.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM731345(US12281099, Example I-063)
Affinity DataIC50: 6.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
Go to US Patent