BDBM731151 4-(5-chloro-2-methoxyphenyl)-N-[6-(5-cyclopropylpyridin-2-yl)thiazolo[4,5-b]pyrazin-2-yl]-6-methylpyridine-3-carboxamide ::US20250122221, Compound 77

SMILES COc1ccc(Cl)cc1-c1cc(C)ncc1C(=O)Nc1nc2ncc(-c3ccc(C4CC4)cn3)nc2s1

InChI Key InChIKey=PSQAOXMVJPMSDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731151   

TargetDNA polymerase theta(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM731151(4-(5-chloro-2-methoxyphenyl)-N-[6-(5-cyclopropylpy...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent