BDBM731148 N-(6-(4-cyanophenyl)thiazolo[4,5-b]pyrazin-2-yl)-5'-(difluoromethoxy)-2',6-dimethyl-[4,4'-bipyridine]-3-carboxamide ::US20250122221, Compound 74

SMILES Cc1cc(-c2cc(C)ncc2C(=O)Nc2nc3ncc(-c4ccc(C#N)cc4)nc3s2)c(OC(F)F)cn1

InChI Key InChIKey=AUKLPDWPBJTXKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731148   

TargetDNA polymerase theta(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM731148(N-(6-(4-cyanophenyl)thiazolo[4,5-b]pyrazin-2-yl)-5...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent