BDBM731147 N-(6-(4-cyanophenyl)thiazolo[4,5-b]pyrazin-2-yl)-5'-methoxy-6-methyl-2'-(trifluoromethyl)-[4,4'-bipyridine]-3-carboxamide ::US20250122221, Compound 73

SMILES COc1cnc(C(F)(F)F)cc1-c1cc(C)ncc1C(=O)Nc1nc2ncc(-c3ccc(C#N)cc3)nc2s1

InChI Key InChIKey=QMGXZDUCIITEJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731147   

TargetDNA polymerase theta(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM731147(N-(6-(4-cyanophenyl)thiazolo[4,5-b]pyrazin-2-yl)-5...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent