BDBM731066 US20250122202, Example 71

SMILES CN1CCN(c2ccc(Nc3nc(NC45CC6CC(C4)C(O)C(C6)C5)c4c(C(=O)c5ccc(F)cc5)c[nH]c4n3)cc2)CC1

InChI Key InChIKey=CWXFKPWTGCJWQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 731066   

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Shandong New Time Pharmaceutical

US Patent
LigandPNGBDBM731066(US20250122202, Example 71)
Affinity DataIC50: 9.27nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical

US Patent
LigandPNGBDBM731066(US20250122202, Example 71)
Affinity DataIC50: 4.54nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent