BDBM7308 14-bromo-6-methoxy-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one::9-bromo-4-methoxypaullone::CHEMBL330398::NSC 702373::Paullone Analog 47

SMILES COc1cccc2-c3[nH]c4ccc(Br)cc4c3CC(=O)Nc12

InChI Key InChIKey=IZRNPQQLTKFPRZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 7308   

LigandPNGBDBM7308(NSC 702373 | CHEMBL330398 | 9-bromo-4-methoxypaull...)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7308(NSC 702373 | CHEMBL330398 | 9-bromo-4-methoxypaull...)
Affinity DataIC50: 4.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7308(NSC 702373 | CHEMBL330398 | 9-bromo-4-methoxypaull...)
Affinity DataIC50: 1.60E+4nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
UniversitäT Hamburg

Curated by ChEMBL
LigandPNGBDBM7308(NSC 702373 | CHEMBL330398 | 9-bromo-4-methoxypaull...)
Affinity DataIC50: 2.50E+5nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM7308(NSC 702373 | CHEMBL330398 | 9-bromo-4-methoxypaull...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of CDK1/cyclin B expressed in M phase starfish oocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM7308(NSC 702373 | CHEMBL330398 | 9-bromo-4-methoxypaull...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GSK3-beta expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed