BDBM7303 9-bromo-12-(tert-butyloxycarbonyl)-paullone::CHEMBL100312::NSC 703057::Paullone Analog 42::tert-butyl 14-bromo-9-oxo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaene-18-carboxylate

SMILES CC(C)(C)OC(=O)n1c-2c(CC(=O)Nc3ccccc-23)c2cc(Br)ccc12

InChI Key InChIKey=XHZYYJIRPPAMPY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7303   

LigandPNGBDBM7303(NSC 703057 | CHEMBL100312 | 9-bromo-12-(tert-butyl...)
Affinity DataIC50: 7.00E+4nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7303(NSC 703057 | CHEMBL100312 | 9-bromo-12-(tert-butyl...)
Affinity DataIC50: 8.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7303(NSC 703057 | CHEMBL100312 | 9-bromo-12-(tert-butyl...)
Affinity DataIC50: 2.30E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
UniversitäT Hamburg

Curated by ChEMBL
LigandPNGBDBM7303(NSC 703057 | CHEMBL100312 | 9-bromo-12-(tert-butyl...)
Affinity DataIC50: 7.00E+4nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed