BDBM7302 2-iodo-9-trifluoromethylpaullone::4-iodo-14-(trifluoromethyl)-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one::CHEMBL121957::NSC 707623::Paullone Analog 41

SMILES FC(F)(F)c1ccc2[nH]c-3c(CC(=O)Nc4ccc(I)cc-34)c2c1

InChI Key InChIKey=BHZJERIYLOTNFQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7302   

LigandPNGBDBM7302(4-iodo-14-(trifluoromethyl)-8,18-diazatetracyclo[9...)
Affinity DataIC50: 700nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7302(4-iodo-14-(trifluoromethyl)-8,18-diazatetracyclo[9...)
Affinity DataIC50: 7.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7302(4-iodo-14-(trifluoromethyl)-8,18-diazatetracyclo[9...)
Affinity DataIC50: 2.20E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7302(4-iodo-14-(trifluoromethyl)-8,18-diazatetracyclo[9...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Cyclin-dependent kinase 1-cyclin B from Starfish oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed