BDBM729760 US20250101040, Compound M21

SMILES Cc1nn(C2CCNCC2)c(C)c1-c1cc(N2CC3CCC(C2)O3)nc2c(-c3ccn[nH]3)cnn12

InChI Key InChIKey=YBPYPRTZMVVXLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 729760   

TargetSerine/threonine-protein kinase ATR(Human)
Jiangsu Yayo Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 729760BDBM729760(US20250101040, Compound M21)
Affinity DataIC50: 22nMAssay Description:The amount of phosphorylated P53 protein was determined using a time-resolved fluorescence system. Before the starting of the experiment, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Jiangsu Yayo Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 729760BDBM729760(US20250101040, Compound M21)
Affinity DataIC50: 22nMAssay Description:Inhibition of ATR (unknown origin) assessed as reduction in p53 phosphorylation level incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed