BDBM729578 US20250101020, Example 6

SMILES [2H]C([2H])([2H])N1c2cnc(Nc3ccc4c(n3)c(-c3cnn(C(F)(F)F)c3)nn4C)cc2[C@]2(C[C@@H](CNC(=O)OC)C2)C1=O

InChI Key InChIKey=HADDSBZJTGWQRA-FIBGUPNXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 729578   

LigandPNGBDBM729578(US20250101020, Example 6)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Incyte

US Patent
LigandPNGBDBM729578(US20250101020, Example 6)
Affinity DataIC50: 2.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
Go to US Patent