BDBM729454 N-(5-(3-benzyl-1-((1r,4S)-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)ureido)-2-((S)-3,4-dimethylpiperazin-1-yl)-3-fluorophenyl)acrylamide::US20250100994, Compound YJZ8070

SMILES C=CC(=O)Nc1cc(N(C(=O)NCc2ccccc2)[C@H]2CC[C@H](Nc3ccc(C#N)cn3)CC2)cc(F)c1N1CCN(C)[C@@H](C)C1

InChI Key InChIKey=DUOIXHFOJLQSIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 729454   

TargetCyclin-dependent kinase 12(Human)
University of Michigan

US Patent
LigandPNGBDBM729454(N-(5-(3-benzyl-1-((1r,4S)-4-((5-cyanopyridin-2-yl)...)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 13(Human)
University of Michigan

US Patent
LigandPNGBDBM729454(N-(5-(3-benzyl-1-((1r,4S)-4-((5-cyanopyridin-2-yl)...)
Affinity DataIC50: 32.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
Go to US Patent