BDBM7293 (E)-3-(6-oxo-9-trifluoromethyl-5,6,7,12-tetrahydro-indolo[3,2-d][1]benzazepin-2-yl)-acrylic acid methyl ester::CHEMBL121958::NSC 707621::Paullone Analog 32::methyl (2E)-3-[9-oxo-14-(trifluoromethyl)-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-4-yl]prop-2-enoate

SMILES COC(=O)\C=C\c1ccc2NC(=O)Cc3c([nH]c4ccc(cc34)C(F)(F)F)-c2c1

InChI Key InChIKey=DJCQWLAUTLNODY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7293   

LigandPNGBDBM7293(CHEMBL121958 | (E)-3-(6-oxo-9-trifluoromethyl-5,6,...)
Affinity DataIC50: 4.30E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7293(CHEMBL121958 | (E)-3-(6-oxo-9-trifluoromethyl-5,6,...)
Affinity DataIC50: 1.30E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7293(CHEMBL121958 | (E)-3-(6-oxo-9-trifluoromethyl-5,6,...)
Affinity DataIC50: 900nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7293(CHEMBL121958 | (E)-3-(6-oxo-9-trifluoromethyl-5,6,...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of Cyclin-dependent kinase 1-cyclin B from Starfish oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed