BDBM7289 14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,8,12(17),13,15-octaene-9-hydroxylamine::9-bromo-7,12-dihydro-6-(hydroxyamino)-indolo[3,2-d][1]benzazepine::CHEMBL98275::Paullone Analog 28

SMILES ONC1=Nc2ccccc2-c2[nH]c3ccc(Br)cc3c2C1

InChI Key InChIKey=AGVIFWRZNWSNSR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7289   

LigandPNGBDBM7289(CHEMBL98275 | 9-bromo-7,12-dihydro-6-(hydroxyamino...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7289(CHEMBL98275 | 9-bromo-7,12-dihydro-6-(hydroxyamino...)
Affinity DataIC50: 2.10E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7289(CHEMBL98275 | 9-bromo-7,12-dihydro-6-(hydroxyamino...)
Affinity DataIC50: 750nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
UniversitäT Hamburg

Curated by ChEMBL
LigandPNGBDBM7289(CHEMBL98275 | 9-bromo-7,12-dihydro-6-(hydroxyamino...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed