BDBM72842 MLS001211140::N-(3-Hydroxy-phenyl)-3-[5-(4-methoxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-propionamide::N-(3-hydroxyphenyl)-3-[(5Z)-4-keto-5-p-anisylidene-2-thioxo-thiazolidin-3-yl]propionamide::N-(3-hydroxyphenyl)-3-[(5Z)-5-[(4-methoxyphenyl)methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]propanamide::N-(3-hydroxyphenyl)-3-[(5Z)-5-[(4-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanamide::N-(3-hydroxyphenyl)-3-[(5Z)-5-[(4-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]propanamide::SMR000514408::cid_2046326

SMILES COc1ccc(\C=C2/SC(=S)N(CCC(=O)Nc3cccc(O)c3)C2=O)cc1

InChI Key InChIKey=KPNUJDBZEVRYLO-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 72842   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM72842(cid_2046326 | SMR000514408 | N-(3-hydroxyphenyl)-3...)
Affinity DataEC50:  5.88E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetATP-dependent RNA helicase DDX3X(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM72842(cid_2046326 | SMR000514408 | N-(3-hydroxyphenyl)-3...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to DDX3X (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed