BDBM728169 (2R,5S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- 4-[5-(ethanesulfonyl) pyrimidin-2-yl]-2,5- dimethylpiperazine-1- carboxamide::US20250092022, Compound 5

SMILES CCS(=O)(=O)c1cnc(N2C[C@@H](C)N(C(=O)NC3CC4(C3)CN(Cc3ccccc3)C4)C[C@@H]2C)nc1

InChI Key InChIKey=YAHDSCSDNTWCPT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728169   

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728169((2R,5S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent