BDBM727114 US20250092017, Compound P30

SMILES CC(C)c1ccc(N2CC(NS(C)(=O)=O)C2)c2cnc(Nc3ccnc(N4CCC(O)C(F)(F)C4)n3)cc12

InChI Key InChIKey=PAFIYXCHGABIBH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 727114   

TargetEpidermal growth factor receptor(Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandPNGBDBM727114(US20250092017, Compound P30)
Affinity DataIC50: 18.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandPNGBDBM727114(US20250092017, Compound P30)
Affinity DataIC50: 3.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [L858R,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandPNGBDBM727114(US20250092017, Compound P30)
Affinity DataIC50: 4.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandPNGBDBM727114(US20250092017, Compound P30)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent