BDBM727048 N—[(S)-(4,4-Difluorocyclohexyl)-[7-[(1S)-2-methoxy-1-[(4S)-2-oxo-4-(trifluoromethyl)imidazolidin-1-yl]ethyl]imidazo[1,2-b]pyridazin-2-yl]methyl]-4-methyl-1,2,5-oxadiazole-3-carboxamide::US12252491, Example 24

SMILES COC[C@H](c1cnn2cc([C@@H](NC(=O)c3nonc3C)C3CCC(F)(F)CC3)nc2c1)N1C[C@@H](C(F)(F)F)NC1=O

InChI Key InChIKey=MVWVCLAORBNXSD-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 727048   

LigandPNGBDBM727048(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[(1S)-2-methoxy...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
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Date in BDB:
7/22/2025
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