BDBM72700 9-acridinamine;hydrate;hydrochloride::9-aminoacridine::Acridin-9-ylamine::MLS000780068::SMR000420251::US20240246941, Compound SJ000285450::acridin-9-amine;hydrate;hydrochloride::acridin-9-ylamine;hydrate;hydrochloride::cid_2723598

SMILES Nc1c2ccccc2nc2ccccc12

InChI Key InChIKey=XJGFWWJLMVZSIG-UHFFFAOYSA-N

Data  1 KI  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 72700   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM72700(cid_2723598 | 9-aminoacridine | acridin-9-amine;hy...)
Affinity DataEC50:  4.13E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetProbable global transcription activator SNF2L2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM72700(cid_2723598 | 9-aminoacridine | acridin-9-amine;hy...)
Affinity DataEC50:  3.37E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM72700(cid_2723598 | 9-aminoacridine | acridin-9-amine;hy...)
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant human NQO2 expressed in Escherichia coli using DCPIP as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM72700(cid_2723598 | 9-aminoacridine | acridin-9-amine;hy...)
Affinity DataIC50: 450nMAssay Description:Inhibition of NQO2 in human SKOV3 cells assessed as reduction in cell viability in presence of 1 uM CB1954 and EPR incubated for 24 hrs measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM72700(cid_2723598 | 9-aminoacridine | acridin-9-amine;hy...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM72700(cid_2723598 | 9-aminoacridine | acridin-9-amine;hy...)
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMelanoma-associated antigen E1(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL, INC.

US Patent
LigandPNGBDBM72700(cid_2723598 | 9-aminoacridine | acridin-9-amine;hy...)
Affinity DataIC50: 7.55E+4nMAssay Description:The TR-FRET assay buffer with a formula of 50 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA and 1 mM DTT was freshly prepared before each experiment. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent

TargetIonotropic glutamate receptor subunit Delta2(African clawed frog)
State University of New York

Curated by PDSP Ki Database
LigandPNGBDBM72700(cid_2723598 | 9-aminoacridine | acridin-9-amine;hy...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2012
Entry Details Article
PubMed