BDBM726021 US20250074919, Example A1

SMILES Cn1cc(-c2cccc(NC(=O)c3cc4oc(N5CCOCC5)nc4nc3N3CC[C@@H](O)C3)n2)cn1

InChI Key InChIKey=FLRKDVVLCWANKY-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 726021   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM726021(US20250074919, Example A1)
Affinity DataIC50: 405nMAssay Description:Table 2: Prepare Ix kinase base buffer and stop buffer for testing kinases: (1) base buffer: 50 mM HEPES (pH 7.5), 0.0015% Brij-35; (2) stop buffer: ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Accro Bioscience (HK)

US Patent
LigandPNGBDBM726021(US20250074919, Example A1)
Affinity DataKd:  29nMAssay Description:Table 3: The Equilibrium dissociation constant reflected the test compound's kinase binding (Kd). The KINOMEscan, a site-directed competition bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent