BDBM725769 US20250074910, Example 58-1b

SMILES CCN(C(=O)c1cc(F)ccc1Oc1nncnc1N1CC2(CCN(C[C@H]3CC[C@@]4(CC3)CC(=O)[C@H](C(C)(C)O)C4)CC2)C1)C(C)C

InChI Key InChIKey=JDRVFCKYBYIWSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 725769   

TargetHistone-lysine N-methyltransferase 2A(Human)
Hitgen

US Patent
LigandPNGBDBM725769(US20250074910, Example 58-1b)
Affinity DataIC50: 5.90nMAssay Description:The inhibition of Menin/MLL-4-43 peptide interaction by small molecule inhibitors was quantitatively detected by fluorescence polarization competitio...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2025
Entry Details
Go to US Patent