BDBM725264 3-(4-(ethylsulfonamido)-3-((4- fluorobenzyl)oxy)phenyl) 5-((5-methoxypyrazin-2- yl)amino)-1H-pyrazole-4- carboxamide::US20250074891, Compound 14

SMILES CCS(=O)(=O)Nc1ccc(-c2n[nH]c(Nc3cnc(OC)cn3)c2C(N)=O)cc1OCc1ccc(F)cc1

InChI Key InChIKey=XNRGLKCZSMTDML-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 725264   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM725264(3-(4-(ethylsulfonamido)-3-((4- fluorobenzyl)oxy)ph...)
Affinity DataKd: <10nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM725264(3-(4-(ethylsulfonamido)-3-((4- fluorobenzyl)oxy)ph...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM725264(3-(4-(ethylsulfonamido)-3-((4- fluorobenzyl)oxy)ph...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2025
Entry Details
Go to US Patent