BDBM725044 N-((R)-2-(2-((1R,5S,6s)-3- oxabicyclo[3.1.0]hexane-6- carboxamido)pyridin-4-yl)- 6,7,8,9-tetrahydro-5H- benzo[7]annulen-5-yl)-3- (tert-butyl)-1,2,4- oxadiazole-5-carboxamide::US12240838, Compound 46

SMILES CC(C)(C)c1noc(C(=O)N[C@@H]2CCCCc3cc(-c4ccnc(NC(=O)[C@@H]5[C@@H]6COC[C@@H]65)c4)ccc32)n1

InChI Key InChIKey=HIRVSCYUFBRDCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 725044   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM725044(N-((R)-2-(2-((1R,5S,6s)-3- oxabicyclo[3.1.0]hexane...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2025
Entry Details
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