BDBM724721 N-((1r,4r)-4-(3- (difluoromethoxy)- azetidin-1-yl)cyclo- hexyl)-3-methyl-1- neopentyl-1H-thieno [2,3-c]pyrazole-5- carboxamide::US20250066383, Compound II-42

SMILES Cc1nn(CC(C)(C)C)c2sc(C(=O)N[C@H]3CC[C@H](N4CC(OC(F)F)C4)CC3)cc12

InChI Key InChIKey=GYHCLDQDLMMTCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724721   

LigandPNGBDBM724721(N-((1r,4r)-4-(3- (difluoromethoxy)- azetidin-1-yl)...)
Affinity DataIC50: 10nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

LigandPNGBDBM724721(N-((1r,4r)-4-(3- (difluoromethoxy)- azetidin-1-yl)...)
Affinity DataIC50: 10nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent