BDBM724708 N-((1r,3r)-3-(4-acet- ylpiperazin-1-yl)- cyclobutyl)-1-(4,4- difluorocyclohexyl)- 3-methyl-1H-thieno [2,3-c]pyrazole-5- carboxamide::US20250066383, Compound II-29

SMILES CC(=O)N1CCN([C@H]2C[C@H](NC(=O)c3cc4c(C)nn(C5CCC(F)(F)CC5)c4s3)C2)CC1

InChI Key InChIKey=HZISGJKHTMGPJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724708   

LigandPNGBDBM724708(N-((1r,3r)-3-(4-acet- ylpiperazin-1-yl)- cyclobuty...)
Affinity DataIC50: 20nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
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LigandPNGBDBM724708(N-((1r,3r)-3-(4-acet- ylpiperazin-1-yl)- cyclobuty...)
Affinity DataIC50: 20nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent