BDBM724690 1-(4,4-difluorocyclo- hexyl)-N-((1r,4r)-4- (4-(2,2-difluoroeth- yl)piperazin-1-yl)- cyclohexyl)-3-meth- yl-1H-thieno[2,3-c] pyrazole-5-carbox- amide::US20250066383, Compound II-11

SMILES Cc1nn(C2CCC(F)(F)CC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCN(CC(F)F)CC4)CC3)cc12

InChI Key InChIKey=SXIXQJGZSUMFHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724690   

LigandPNGBDBM724690(1-(4,4-difluorocyclo- hexyl)-N-((1r,4r)-4- (4-(2,2...)
Affinity DataIC50: 20nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

LigandPNGBDBM724690(1-(4,4-difluorocyclo- hexyl)-N-((1r,4r)-4- (4-(2,2...)
Affinity DataIC50: 20nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent