BDBM724689 1-(4,4-difluorocyclo- hexyl)-N-((1r,4r)-4- (4-isopropylpiper- azin-1-yl)cyclohex- yl)-3-methyl-1H- thieno[2,3-c]pyra- zole-5-carboxamide::US20250066383, Compound II-10

SMILES Cc1nn(C2CCC(F)(F)CC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCN(C(C)C)CC4)CC3)cc12

InChI Key InChIKey=HBLVAMMEZDPAJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724689   

LigandPNGBDBM724689(1-(4,4-difluorocyclo- hexyl)-N-((1r,4r)-4- (4-isop...)
Affinity DataIC50: 10nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
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LigandPNGBDBM724689(1-(4,4-difluorocyclo- hexyl)-N-((1r,4r)-4- (4-isop...)
Affinity DataIC50: 10nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent