BDBM724675 N-((1r,4r)-4-(4-acetyl- piperazin-1-yl)cyclo- hexyl)-1-(2-chloro- phenyl)-3-methyl-1H- thieno[2,3-c]pyrazole- 5-carboxamide::US20250066383, Compound I-4

SMILES CC(=O)N1CCN([C@H]2CC[C@H](NC(=O)c3cc4c(C)nn(-c5ccccc5Cl)c4s3)CC2)CC1

InChI Key InChIKey=NBRDCBWDWLAWCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724675   

LigandPNGBDBM724675(N-((1r,4r)-4-(4-acetyl- piperazin-1-yl)cyclo- hexy...)
Affinity DataIC50: 10nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

LigandPNGBDBM724675(N-((1r,4r)-4-(4-acetyl- piperazin-1-yl)cyclo- hexy...)
Affinity DataIC50: 10nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent