BDBM724646 US20250066377, Example 32

SMILES COC[C@H]1CCN(c2ccc3c(-c4ccccc4C)cc(=O)oc3n2)C1

InChI Key InChIKey=IPWKLVTXIJPYFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724646   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724646(US20250066377, Example 32)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent