BDBM724635 US20250066377, Example 21

SMILES O=c1cc(-c2ccc(F)cc2Cl)c2ccc(N3CCOCC3)nc2o1

InChI Key InChIKey=DRSDSXJWIAXDAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724635   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724635(US20250066377, Example 21)
Affinity DataIC50: 3.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent