BDBM724614 US20250066372, Example 10

SMILES CN(C)C(=O)c1cc2cnc(N[C@@H]3CCOC[C@H]3O)nc2n1-c1ccc2c(c1)C1(CCC2N(C)C)CC1

InChI Key InChIKey=PHYKSMUMABKXEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724614   

LigandPNGBDBM724614(US20250066372, Example 10)
Affinity DataIC50: 13nMAssay Description:Compounds disclosed herein were tested for inhibition of CDK4/Cyclin D1 or CDK6/Cyclin D3 kinase in an assay based on the time-resolved fluorescence-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

LigandPNGBDBM724614(US20250066372, Example 10)
Affinity DataIC50: 584nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent