BDBM724608 US20250066372, Example 4

SMILES CN(C)Cc1ccc(-n2c(C(=O)N(C)C)cc3cnc(N[C@@H]4CCOC[C@H]4O)nc32)cc1C1CC1

InChI Key InChIKey=KFALTJHKAYBGIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724608   

LigandPNGBDBM724608(US20250066372, Example 4)
Affinity DataIC50: 9.70nMAssay Description:Compounds disclosed herein were tested for inhibition of CDK4/Cyclin D1 or CDK6/Cyclin D3 kinase in an assay based on the time-resolved fluorescence-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

LigandPNGBDBM724608(US20250066372, Example 4)
Affinity DataIC50: 778nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent