BDBM724599 2-(morpholin-4-yl)-8-(trifluoromethyl)-N-({5-[6-(trifluoromethyl) pyridin-3-yl]-1H-imidazol-2-yl}methyl)pyrazolo[1,5-a][1,3,5]triazin-4-amine::US20250066370, Example 24

SMILES FC(F)(F)c1ccc(-c2cnc(CNc3nc(N4CCOCC4)nc4c(C(F)(F)F)cnn34)[nH]2)cn1

InChI Key InChIKey=KRXJZQJGWWTQFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 724599   

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Deutsches Krebsforschungszentrum

US Patent
LigandPNGBDBM724599(2-(morpholin-4-yl)-8-(trifluoromethyl)-N-({5-[6-(t...)
Affinity DataIC50: 15.1nMAssay Description:For the assay 50 nanoL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtit...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
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TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Deutsches Krebsforschungszentrum

US Patent
LigandPNGBDBM724599(2-(morpholin-4-yl)-8-(trifluoromethyl)-N-({5-[6-(t...)
Affinity DataIC50: 7.82E+3nMAssay Description:For the assay 50 nanoL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Deutsches Krebsforschungszentrum

US Patent
LigandPNGBDBM724599(2-(morpholin-4-yl)-8-(trifluoromethyl)-N-({5-[6-(t...)
Affinity DataIC50: 3.56E+3nMAssay Description:For the assay 50 nanoL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtit...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent