BDBM724566 (S)—N-(3-chloro-2,4-difluorophenyl)-N-methyl-2-oxo-3-(4-(trifluoromethyl)thieno[2,3-d]pyridin-2-yl)imidazolidine-4-carboxamide ::US20250066368, Compound 24

SMILES CN(C(=O)[C@@H]1CNC(=O)N1c1nc(C(F)(F)F)c2ccsc2n1)c1ccc(F)c(Cl)c1F

InChI Key InChIKey=WVXWVHBNMGFDQB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724566   

TargetDNA polymerase theta [1792-2590](Homo sapiens (Human))
Shanghai Apeiron Therapeutics Company

US Patent
LigandPNGBDBM724566((S)—N-(3-chloro-2,4-difluorophenyl)-N-methyl-2-oxo...)
Affinity DataIC50: 50nMAssay Description:The ability of compounds to inhibit Pol 0 polymerase activity was determined by the PicoGreen method in vitro.The His-TEV-SUMO-tagged Polθ protein (a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
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