BDBM724551 US20250066368, Compound 9b

SMILES CN(C(=O)[C@H]1CNC(=O)N1c1cc(C(F)(F)F)c2c(n1)CC=C2)C1=C(F)C(Cl)C(F)C=C1

InChI Key InChIKey=ASYPNIMMWRSUAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724551   

TargetDNA polymerase theta [1792-2590](Homo sapiens (Human))
Shanghai Apeiron Therapeutics Company

US Patent
LigandPNGBDBM724551(US20250066368, Compound 9b)
Affinity DataIC50: 50nMAssay Description:The ability of compounds to inhibit Pol 0 polymerase activity was determined by the PicoGreen method in vitro.The His-TEV-SUMO-tagged Polθ protein (a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent