BDBM724491 US20250066363, Example 23

SMILES CC[C@@H]1CN(c2nc(=O)n(C)c3c2nnn3C[C@H]2CCCO2)[C@@H](C)CN1[C@@H](c1ccc(Cl)cc1)[C@@H]1CC1(F)F

InChI Key InChIKey=PAJCZDCGGGKXCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724491   

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM724491(US20250066363, Example 23)
Affinity DataIC50: 10nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM724491(US20250066363, Example 23)
Affinity DataIC50: 10nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent