BDBM724489 US20250066363, Example 21

SMILES Cc5nc4c(N3C[C@@H](C)N(C(c1ccc(C(F)(F)F)cc1)[C@H]2CC2(F)F)C[C@@H]3C)nc(=O)n(C)c4n5C[C@@H]6CCCO6

InChI Key InChIKey=NHLKVVXWIXEPTQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724489   

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM724489(US20250066363, Example 21)
Affinity DataIC50: 10nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM724489(US20250066363, Example 21)
Affinity DataIC50: 10nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent