BDBM724475 US20250066363, Example 7

SMILES C[C@@H]1CN(c2nc(=O)n(C)c3c2cnn3C)[C@@H](C)CN1C(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=IHXFKEMKLJZLON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724475   

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM724475(US20250066363, Example 7)
Affinity DataIC50: 10nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM724475(US20250066363, Example 7)
Affinity DataIC50: 1.00E+3nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent