BDBM724235 US20250066345, Compound I-42

SMILES COc1cccc(CNc2cnc(S(=O)(=O)Nc3nc(-c4ccc(F)c(Cl)c4)c(F)s3)c(-c3ccccc3)c2)c1O

InChI Key InChIKey=OPMPHESLBBMUMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724235   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
Veralox Therapeutics

US Patent
LigandPNGBDBM724235(US20250066345, Compound I-42)
Affinity DataIC50: 250nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent