BDBM724219 US20250066345, Compound I-11

SMILES COc1cccc(CN(C)c2ccc(S(=O)(=O)Nc3nc(-c4ccc(F)c(F)c4)c(F)s3)nc2)c1O

InChI Key InChIKey=DSZPQLUVAPVSPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724219   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
Veralox Therapeutics

US Patent
LigandPNGBDBM724219(US20250066345, Compound I-11)
Affinity DataIC50: 625nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent